BiophysicsbioRxiv
Single-molecule analysis of the entire perfringolysin O poreformation pathway
C. Mc Guinness, J. Walsh, C. Bayly-Jones…·T. Boecking
This study uses single-molecule fluorescence imaging to analyze the kinetics of PFO pore formation, revealing that membrane insertion is kinetically controlled.
DOI 10.7554/elife.74901