Author

T. Boecking

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

D. A. Jacques· 2 shared G. J. Towers· 2 shared J. Walsh· 2 shared M. W. Parker· 2 shared A. J. Tuckwell· 1 shared A. JEGOU· 1 shared A. Tuckwell· 1 shared C. Bayly-Jones· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

D. A. Jacques

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores

C. F. Dickson, S. Hertel, J. Ruan, N. Ariotti, A. Tuckwell, N. Li, S. Al-Izzi, E. Sierecki, Y. Gambin, R. G. Morris, G. J. Towers, T. Boecking, D. A. Jacques

This paper shows how the HIV capsid mimics karyopherins to penetrate nuclear pores by interacting with FG-motifs, enabling it to bypass the size limit of the nuclear pore complex.

bioRxiv · Mar 23, 2023 · PreprintBiochemistry

Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

K. M. R. Faysal, J. C. Walsh, N. Renner, C. L. Marquez, V. Shah, A. J. Tuckwell, M. P. Christie, M. W. Parker, S. G. Turville, L. James, G. J. Towers, D. A. Jacques, T. Boecking

This study shows Lenacapavir's antiviral effect comes from hyperstabilizing the HIV-1 capsid lattice, leading to loss of compartmentalization and capsid failure.

bioRxiv · Sep 21, 2022Biophysics

Single-molecule analysis of the entire perfringolysin O poreformation pathway

C. Mc Guinness, J. Walsh, C. Bayly-Jones, M. Dunstone, C. Morton, M. Christie, M. W. Parker, T. Boecking

This study uses single-molecule fluorescence imaging to analyze the kinetics of PFO pore formation, revealing that membrane insertion is kinetically controlled.

bioRxiv · Oct 19, 2021Biophysics

Dynamics of Tpm1.8 domains on actin filaments with single moleculeresolution

I. Bareja, H. Wioland, M. Janco, P. R. Nicovich, A. JEGOU, G. Romet-Lemonne, J. Walsh, T. Boecking

This study uses fluorescence microscopy and modeling to quantify Tpm1.8 binding kinetics on actin filaments, revealing independent decoration of actin strands and asymmetric domain dynamics.

bioRxiv · Jun 15, 2020Biophysics