Author

C. Reinhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Bosmann· 4 shared A. Sharma· 2 shared J. Roewe· 2 shared S. Walachowski· 2 shared V. Krenzlin· 2 shared A. Saghatelian· 1 shared B. Cravatt· 1 shared B. Ghosh· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersImmunology

M. Bosmann

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Author profile →

5 papers

Recent·Most cited

Immunomodulation of Neutrophil Granulocyte Functions by Bacterial Polyphosphates

V. Krenzlin, J. Schoeche, S. Walachowski, C. Reinhardt, M. P. Radsak, M. Bosmann

This study shows that bacterial long-chain polyphosphates modulate neutrophil function, reducing inflammation and immune responses in mice and humans.

bioRxiv · Dec 21, 2022Immunology

Proteomic discovery of chemical probes that perturb protein complexes in human cells

M. Lazear, J. Remsberg, M. Jaeger, K. Rothamel, H.-l. Her, K. DeMeester, E. Njomen, S. Hogg, J. Rahman, L. Whitby, S. J. Won, M. Schafroth, D. Ogasawara, M. Yokoyama, G. Lindsey, , B. Cravatt

This study develops a proteomic strategy to identify chemical probes that perturb protein complexes in human cells by analyzing electrophilic compounds' effects on protein interactions.

bioRxiv · Dec 12, 2022Biochemistry

Bacterial Polyphosphates Induce CXCL4 and Synergize with Complement Anaphylatoxin C5a in Lung Injury

J. Roewe, S. Walachowski, A. Sharma, K. A. Berthiaume, C. Reinhardt, M. Bosmann

This study shows that long-chain bacterial polyphosphates induce CXCL4 release from macrophages and synergize with C5a to cause lung injury.

bioRxiv · Jul 5, 2022Immunology

Proteome Microarray Screening Identifies Human Polyphosphate-Binding Proteins in the Phosphatidylinositol Signaling Pathway

V. Krenzlin, J. Roewe, M. Strueve, M. Martinez-Negro, C. Reinhardt, S. Morsbach, M. Bosmann

The paper identifies human polyphosphate-binding proteins using a proteome microarray screen, highlighting DAB1 and PIP4K2B in the phosphatidylinositol signaling pathway.

bioRxiv · Dec 10, 2021 · PreprintImmunology

IL-27 enhances the lymphocyte mediated innate resistance to primary hookworm infection in the lungs

J. B. Noon, A. Sharma, J. Platten, L. J. Quinton, C. Reinhardt, M. Bosmann

This study shows IL-27 reduces hookworm infection and lung damage by enhancing lymphocyte responses in mice.

bioRxiv · Aug 12, 2020 · PreprintImmunology