Author

C. Soun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. R. Engel· 2 shared A. Bazarna· 1 shared A. Dixit· 1 shared A. Paschen· 1 shared A. Urbanek· 1 shared A. W. Chan· 1 shared A.-L. Beerlage· 1 shared B. Scheffler· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

D. R. Engel

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Author profile →

2 papers

Recent·Most cited

Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression

P. F. Cheung, J. Yang, K. Krengel, K. Althoff, C. Yip, E. H. Siu, L. W. Ng, K. S. Lang, L. Cham, D. R. Engel, C. Soun, I. Cima, B. Scheffler, J. K. Striefler, M. Sinn, , J. T. Siveke

This study shows that tumor-derived progranulin (PGRN) promotes immune evasion in pancreatic ductal adenocarcinoma by reducing MHC class I expression, and blocking PGRN enhances immune response and slows tumor progression.

bioRxiv · Feb 24, 2021 · PreprintCancer Biology

Relocation of macrophages maintains the barrier function of the urothelium and protects against persistent infection

J. Bottek, C. Soun, J. K. Volke, A. Dixit, S. Thiebes, A.-L. Beerlage, M. Horstmann, A. Urbanek, J. Uszkoreit, M. Eisenacher, T. Bracht, B. Sitek, F. Hoffmann, N. Vijitha, F. von Eggeling, D. R. Engel

The paper shows that macrophage relocation into the urothelium, driven by IL-6 and CX3CL1, helps maintain barrier function and prevent recurrent urinary tract infections.

bioRxiv · Jun 6, 2019 · PreprintImmunology