C. Vogel

Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses

The paper analyzes baseline multi-omic data from influenza vaccine recipients to identify pre-immune states predictive of vaccination responses.

DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies

This study identifies DEK bodies involved in heterochromatin replication and links DEK to SUMO regulation, highlighting its role in chromatin integrity and cancer.

Complex changes in serum protein levels in COVID-19 convalescents

This study identifies changes in serum protein levels in COVID-19 convalescents compared to healthy controls, revealing both similarities and differences with acute phase changes.

Proteomic signatures of the serological response to flu vaccination in a large human cohort study

The paper identifies proteomic signatures associated with seroconversion after flu vaccination in a human cohort, revealing links between protein levels and immune response factors.

Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes

The paper identifies 332 DNA break-dependent phosphorylation sites in yeast meiosis, showing minimal protein level changes despite transcriptional responses.

Sex-specific glycosylation of secreted immunomodulatory proteins in the filarial nematode Brugia malayi

This study identifies sex-specific glycosylation patterns in immunomodulatory proteins of Brugia malayi, suggesting targets for disrupting parasitic transmission.

The oncoprotein DEK affects the outcome of PARP1/2 inhibition during replication stress

This study shows that DEK interacts with PAR to influence replication fork progression under stress, affecting PARP1/2 inhibitor efficacy in cancer cells.