D. R. Jones

Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses

The paper analyzes baseline multi-omic data from influenza vaccine recipients to identify pre-immune states predictive of vaccination responses.

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability

This study identifies CD97 as a targetable vulnerability in glioblastoma through its role in tumor metabolism and signaling, supported by transcriptomic, proteomic, and functional analyses.

Replicative Instability Drives Cancer Progression

This study identifies a pan-cancer class of tumors driven by replicative instability, showing it accelerates cancer progression through genomic changes and transcriptional rewiring.

Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer

The paper profiles single-cell transcriptomes of SCLC subtypes to identify novel tumor and myeloid subpopulations and their associations with metastasis and immune microenvironment changes.

Quantifying fluorescent glycan uptake to elucidate strain-level variability in foraging behaviors of rumen bacteria

The paper uses fluorescent glycan uptake and genomic analyses to study strain-level differences in carbohydrate metabolism among rumen bacteria.