ImmunologybioRxiv
Polypyrimidine Tract Binding Protein 1 regulates the activation of mouse CD8 T cells
V. D'Angeli, E. Monzon-Casanova, L. S. Matheson…·M. Turner
This study shows PTBP1 is essential for optimal expansion and effector function of antigen-specific CD8 T cells, regulating splicing, mRNA abundance, and NFAT protein nuclear accumulation.
DOI 10.1002/eji.202149781