Pharmacology & ToxicologybioRxiv
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
R. Ferreira de Freitas, Y. Liu, M. Szewczyk…·A. Allali-Hassani
This study identifies small-molecule antagonists of the NSD2 PWWP domain that block its interaction with H3K36me2, providing a tool for further investigation of NSD2's role in disease.
DOI 10.1021/acs.jmedchem.0c01768