Magnetically Powered Microwheel Thrombolysis of Occlusive Thrombi in Zebrafish
M. H. H. Pontius, C.-J. Ku, M. J. Osmond, D. Disharoon, Y. Liu, D. W. M. Marr, K. B. Neeves, J. A. Shavit
This paper demonstrates that tPA-functionalized microwheels, guided by magnetic fields, can efficiently dissolve occlusive thrombi in zebrafish larvae, outperforming systemic tPA delivery.
bioRxiv · Sep 11, 2023Bioengineering