A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy
M. Seyedsadr, M. Bang, E. McCarthy, S. Zhang, H.-C. Chen, M. Mohebbi, W. HUGO, J. K. Whitmire, M. G. Lechner, M. Su
The paper identifies IL-21-expressing CD4+ T cells in an inflammatory neuropathy mouse model and shows their role in neuropathy development through clonal expansion and CXCR6-mediated infiltration.
bioRxiv · Jan 7, 2024Immunology