Author

D. Acharya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. A. Amarilla· 1 shared A. A. Khromykh· 1 shared A. Azuar· 1 shared A. Idris· 1 shared A. Isaacs· 1 shared A. Supramaniam· 1 shared B. Liang· 1 shared C. C. Cheng· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. A. Amarilla

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Exploring the Human-Coronavirus protein-protein interaction network from the perspective of a novel host-virus association

D. Acharya, T. K. Dutta

This study analyzes the SARS-CoV2-human protein interaction network, finding that associated human proteins are hubs, part of more complexes, and have slower evolution, potentially contributing to SARS-CoV2's higher infectivity.

bioRxiv · Jan 12, 2024 · PreprintEvolutionary Biology

A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell wall acetylation

M. Özcam, J.-H. Oh, R. Tocmo, D. Acharya, S. Zhang, T. Astmann, M. Heggen, S. Ruiz-Ramirez, F. Li, C. C. Cheng, E. Vivas, F. E. Rey, J. Claesen, T. Bugni, J. Walter, J. P. van Pijkeren

The study identifies a secondary metabolite produced by L. reuteri that mediates intraspecies antagonism, with resistance linked to cell wall acetylation.

bioRxiv · Jun 11, 2021Microbiology

Complete protection by a single dose skin patch delivered SARS-CoV-2 spike vaccine

C. L. D. McMillan, J. J. Y. Choo, A. Idris, A. Supramaniam, N. Modhiran, A. A. Amarilla, A. Isaacs, S. T. M. Cheung, B. Liang, H. Bielefeldt-Ohmann, A. Azuar, D. Acharya, G. Kelly, G. J. P. Fernando, M. J. Landsberg, , D. A. Muller

A single dose of a SARS-CoV-2 spike vaccine delivered via a high-density microarray patch provides complete protection against a lethal virus challenge.

bioRxiv · May 30, 2021Microbiology

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease

G. Liu, J.-H. Lee, Z. M. Parker, D. Acharya, J. J. Chiang, M. van Gent, W. Riedl, M. E. Davis-Gardner, E. Wies, C. Chiang, M. U. Gack

This study shows ISG15 is essential for MDA5-mediated antiviral responses and is counteracted by SARS-CoV-2's PLpro protease.

bioRxiv · Oct 26, 2020Immunology