Author

M. U. Gack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Liu· 2 shared A. Ensser· 1 shared A. H. Tavares· 1 shared A. Herrmann· 1 shared A. K. O'Connell· 1 shared C. Chiang· 1 shared C.-V. Chin· 1 shared D. Acharya· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

G. Liu

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 13, 2022

Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1Omicron

D.-Y. Chen, D. Kenney, C.-V. Chin…·M. Saeed

This study compares the pathogenicity and immune evasion of an Omicron S-bearing virus with natural Omicron, showing vaccine escape via S mutations but severe disease due to factors outside S.

DOI 10.1101/2022.10.13.512134

mouseexperimental assay

ImmunologybioRxivOct 26, 2020

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease

G. Liu, J.-H. Lee, Z. M. Parker…·M. U. Gack

This study shows ISG15 is essential for MDA5-mediated antiviral responses and is counteracted by SARS-CoV-2's PLpro protease.

DOI 10.1038/s41564-021-00884-1

humanproteomics