An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity
S. Kirchner, V. Lei, P. Kim, M. Patel, J. Shannon, D. Corcoran, D. Hughes, D. Waters, K. Dzirasa, D. Erdmann, J. Coers, A. MacLeod, J. Zhang
This study identifies a circadian rhythm that regulates antiviral immunity in skin, showing that aging disrupts this rhythm and that circadian enhancers can restore antiviral defenses.
bioRxiv · Apr 14, 2023 · PreprintImmunology