Author

D. Fowler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. F. Howard· 1 shared A. Kanouta· 1 shared A. Price· 1 shared A. Southern Navarrete· 1 shared B. Draper· 1 shared C. Gallagher· 1 shared C. J. Tape· 1 shared C. Nattress· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A. F. Howard

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Author profile →

4 papers

Recent·Most cited

Antigen perception in T cells by long-term Erk and NFAT signaling dynamics.

M. J. Wither, W. L. White, S. Pendyala, P. J. Leanza, D. Fowler, H. Y. Kueh

This study shows T cells use long-term Erk and NFAT signaling dynamics to independently encode pMHC affinity and dose, enabling specific transcriptional responses.

bioRxiv · Jun 1, 2023Immunology

OPS-γδ: allogeneic opsonin-secreting γδT cell immunotherapy for solid tumours mediates direct and bystander immunity

D. Fowler, M. Barisa, A. Southern Navarrete, C. Nattress, E. Hawkins, E. Vassalou, A. Kanouta, J. Counsell, E. M. Rota, P. Vlckova, B. Draper, C. J. Tape, K. Chester, J. Anderson, J. Fisher

OPS-γδ cells, engineered to secrete opsonins and stabilized IL15, show enhanced cytotoxicity and bystander activation for solid tumor control.

bioRxiv · Oct 23, 2022 · PreprintImmunology

Profiling of the drug resistance of thousands of Src tyrosine kinase mutants uncovers a regulatory network that couples autoinhibition to catalytic domain dynamics

S. Chakraborty, E. Ahler, J. Simon, L. Fang, Z. Potter, K. Sitko, J. Stephany, M. Guttman, D. Fowler, D. J. Maly

bioRxiv · Dec 5, 2021 · PreprintBiochemistry

The Forget-Me-Not dHCP study: 7 Tesla high resolution diffusion imaging in the unfixed post-mortem neonatal brain

W. Wu, L. Baxter, S. W. Rieger, E. Adams, J. L. R. Andersson, M. C. Andrade, F. Andritsou, M. Bastiani, R. E. Fry, R. Frost, S. Fitzgibbon, S. Foxley, D. Fowler, C. Gallagher, A. F. Howard, , K. L. Miller

The paper describes the Forget-Me-Not dHCP study, which acquires high-resolution diffusion MRI data from unfixed post-mortem neonatal brains and presents preliminary analyses of cortical and white matter structures.

bioRxiv · Jun 24, 2021 · PreprintBioengineering