Author

D. Goulet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. A. Lane· 1 shared A. B. Miller· 1 shared A. Langenbucher· 1 shared A. Ramos· 1 shared A. Regev· 1 shared C. Bray· 1 shared C. E. Koch· 1 shared D. M. Weinstock· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. A. Lane

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Leukemia circulation kinetics revealed through blood exchange method

A. B. Miller, A. Langenbucher, F. H. Rodriguez, L. Lin, C. Bray, S. Duquette, Y. Zhang, D. Goulet, A. A. Lane, D. M. Weinstock, M. T. Hemann, S. R. Manalis

This study uses a blood exchange method in mouse leukemia models to show that leukemia cells circulate longer than solid tumor cells and that microenvironmental factors like E-selectin influence their clearance.

bioRxiv · Sep 3, 2023Cancer Biology

Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.

A. Ramos, C. E. Koch, Y. Liu, R. D. Hellinger, T. Kyung, K. L. Abbott, J. Froese, D. Goulet, K. S. Gordon, R. C. Larson, J. G. Doench, A. Regev, M. G. Vander Heiden, M. V. Maus, M. E. Birnbaum, M. Hemann

This study identifies leukemia-intrinsic resistance mechanisms to CAR-T therapy through in vivo CRISPR screening in a murine B-ALL model, revealing IFNγ/JAK/STAT and antigen processing pathways as key mediators.

bioRxiv · Feb 15, 2022 · PreprintCancer Biology