Author

A. Langenbucher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

M. Lawrence· 2 shared A. A. Lane· 1 shared A. Abbasi· 1 shared A. Amon· 1 shared A. B. Miller· 1 shared A. Desmond· 1 shared A. N. Hata· 1 shared A. Riley· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCancer Biology

M. Lawrence

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4 papers

Recent·Most cited

Leukemia circulation kinetics revealed through blood exchange method

A. B. Miller, A. Langenbucher, F. H. Rodriguez, L. Lin, C. Bray, S. Duquette, Y. Zhang, D. Goulet, A. A. Lane, D. M. Weinstock, M. T. Hemann, S. R. Manalis

This study uses a blood exchange method in mouse leukemia models to show that leukemia cells circulate longer than solid tumor cells and that microenvironmental factors like E-selectin influence their clearance.

bioRxiv · Sep 3, 2023Cancer Biology

APOBEC3A drives acquired resistance to targeted therapies in non-small cell lung cancer

H. Isozaki, A. Abbasi, N. Nikpour, A. Langenbucher, W. Su, M. Stanzione, H. Frisco-Cabanos, F. M. Siddiqui, N. Phan, P. Jalili, S. Oh, D. Timonina, S. Bilton, M. Gomez-Caraballo, H. L. Archibald, , A. N. Hata

This study shows that APOBEC3A mutagenesis driven by targeted therapies promotes drug resistance in non-small cell lung cancer.

bioRxiv · Jan 20, 2021Cancer Biology

Aneuploidy and deregulated DNA damage response define haploinsufficiency in breast tissues of BRCA2 mutation carriers

M. Karaayvaz, R. E. Silberman, A. Langenbucher, S. V. Saladi, K. N. Ross, E. Zarcaro, A. Desmond, M. Yildirim, V. Vivekanandan, H. Ravichandran, R. Mylavagnanam, M. C. Specht, S. Ramaswamy, M. Lawrence, A. Amon, L. W. Ellisen

The paper identifies sub-chromosomal copy number variations and DNA damage in BRCA2 mutation carriers' breast tissues, indicating haploinsufficiency and early carcinogenic changes.

bioRxiv · Aug 8, 2019Cancer Biology

A post-transcriptional program of chemoresistance by AU-rich elements and TTP

S. Lee, D. Micalizzi, S. S. Truesdell, S. I. Bukhari, M. Boukhali, J. Lombardi-Story, Y. Kato, I. Dey-Guha, B. T. Nicholson, M.-K. Choo, D. T. Myers, D. Lee, M. A. Mazzola, R. Raheja, A. Langenbucher, , S. Vasudevan

This study identifies a post-transcriptional mechanism of chemoresistance in leukemia involving AU-rich elements and TTP regulation.

bioRxiv · May 3, 2019 · PreprintCancer Biology