Author

D. Hasson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:DNA methylation· 2

Frequent Co-Authors

S. Carcamo· 4 shared D. Demircioglu· 3 shared E. Bernstein· 3 shared D. K. Singh· 2 shared D. Sun· 2 shared J. A. Aguirre-Ghiso· 2 shared X. Wang· 2 shared A. F. Stewart· 1 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCancer Biology

S. Carcamo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

S. Mzoughi, M. Schwarz, X. Wang, D. Demircioglu, G. Ulukaya, K. Mohammed, F. Di Tullio, C. Company, Y. Dramaretska, M. Leushacke, B. Giotti, T. Lannagan, D. Lozano-Ojalvo, D. Hasson, A. Tsankov, , E. Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

bioRxiv · Dec 10, 2023Cancer Biology

H2A.Z chaperones converge on histone H4 acetylation for melanoma cell proliferation

S. Jostes, C. Vardabasso, J. Dong, S. Carcamo, R. Singh, R. Phelps, A. Meadows, D. Hasson, E. Bernstein

This study shows that H2A.Z chaperones SRCAP, P400, and YL1 regulate H4 acetylation and cell cycle genes in melanoma, with YL1 loss inducing apoptosis and correlating with poor patient outcomes.

bioRxiv · Nov 26, 2023 · PreprintCancer Biology

Cadherin-dependent adhesion is required for muscle stem cell niche anchorage and maintenance

M. Hung, H.-F. Lo, A. G. Beckmann, D. Demircioglu, G. Damle, D. Hasson, G. L. Radice, R. S. Krauss

This study shows that cadherin-catenin adhesion is essential for muscle stem cell niche anchorage and maintenance, as its disruption leads to stem cell depletion through premature differentiation and niche exit.

bioRxiv · Oct 5, 2023Cell Biology

Single Cell RNA-Seq Analysis of Regenerative Drug-Treated Human Pancreatic Islets Identifies A Cycling Alpha Cell Population As Key Beta Cell Progenitors

E. Karakose, X. Wang, P. Wang, S. Carcamo, D. Demircioglu, O. Wood, R. Kang, L. Lambertini, G. Lu, D. K. Scott, A. Garcia-Ocana, C. Argmann, R. Sebra, D. Hasson, A. F. Stewart

This study uses single-cell RNA sequencing to identify cycling alpha cells as key beta cell progenitors in response to DYRK1A inhibitor treatment in human pancreatic islets.

bioRxiv · Sep 7, 2023 · PreprintCell Biology

MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells

D. Sun, D. Filipescu, D. Hasson, D. K. Singh, S. Carcamo, B. Khalil, B. Miles, W. Westra, K. C. Sproll, E. Bernstein, J. A. Aguirre-Ghiso

This study shows macroH2A2 promotes dormancy in disseminated cancer cells, preventing metastasis without requiring known dormancy factors.

bioRxiv · Dec 7, 2021Cancer Biology

Epigenetic reprogramming of DCCs into dormancy suppresses metastasis via restored TGFβ-SMAD4 signaling.

D. K. Singh, E. Farias, S. Carcamo, D. Hasson, D. Sun, J. Cheung, A. R. Nobre, N. Kale, M. S. Sosa, E. Bernstein, J. A. Aguirre-Ghiso

The paper shows that AZA+atRA treatment induces dormancy in DCCs by restoring TGFβ-SMAD4 signaling, suppressing lung metastasis.

bioRxiv · Aug 1, 2021Cancer Biology