Author

H. Wise

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:CUT&Tag· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. Digard· 2 shared A. Forrest· 1 shared A. Tomoiu· 1 shared B. H. Thompson· 1 shared B. Wang· 1 shared C. Sharp· 1 shared D. Hume· 1 shared E. R. Gaunt· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

P. Digard

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy

C. Sharp, B. H. Thompson, T. J. Nash, O. Lee, R. M. Pinto, L. Thorley, Y.-T. Lin, S. Sives, H. Wise, S. M. R. Clohisey, F. Grey, L. Vervelde, P. Simmonds, P. Digard, E. R. Gaunt

This paper engineers an influenza A virus with increased CpG content, showing it is attenuated in mice but replication competent in vaccine propagation systems, suggesting a new strategy for live attenuated vaccines.

bioRxiv · Apr 29, 2022Microbiology

Comprehensive characterisation of molecular host-pathogen interactions in influenza A virus-infected human macrophages

S. Clohisey, N. Parkinson, B. Wang, N. Bertin, H. Wise, A. Tomoiu, K. Summers, P. Carninci, A. Forrest, Y. Hayashizaki, P. Digard, D. Hume, J. K. Baillie, FANTOM 5 Consortium

This study characterizes molecular host-pathogen interactions in influenza A virus-infected human macrophages using CAGE sequencing, revealing snatching preferences and avoidance patterns of host RNAs.

bioRxiv · Jun 17, 2019 · PreprintImmunology