Author

D. J. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. S. Fraser· 2 shared A. Abedi· 1 shared A. J. Devanny· 1 shared A. S. Mankin· 1 shared C. Cerini· 1 shared C. Liu· 1 shared C. Woodward· 1 shared D. Galonic Fujimori· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiophysics

J. S. Fraser

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Microfluidic Quaking-Induced Conversion (Micro-QuIC) for Rapid On-Site Amplification and Detection of Misfolded Proteins

D. J. Lee, P. R. Christenson, G. Rowden, N. C. Lindquist, P. A. Larsen, S.-H. Oh

This paper introduces Micro-QuIC, a microfluidic platform for rapid detection of misfolded proteins, demonstrating faster amplification and visual detection of CWD compared to RT-QuIC.

bioRxiv · Jul 17, 2023 · PreprintBioengineering

Signatures of Jamming in the Cellular Potts Model

A. J. Devanny, D. J. Lee, L. Kampman, L. J. Kaufman

This study identifies signatures of jamming in the Cellular Potts Model by analyzing mobility, diffusion, and cell shape changes under varying adhesion and confinement conditions.

bioRxiv · Jul 10, 2023 · PreprintBiophysics

Functional Ultrasound Imaging of the Human Spinal Cord

K. Agyeman, D. J. Lee, J. Russin, E. I. Kreydin, W. Choi, A. Abedi, V. R. Edgerton, C. Liu, V. Christopoulos

This study uses functional ultrasound imaging to evaluate spinal cord hemodynamics in humans during epidural stimulation, revealing new insights into spinal circuitry and blood flow responses.

bioRxiv · Aug 6, 2022Bioengineering

Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

K. Tsai, V. Stojkovic, D. J. Lee, I. D. Young, T. Szal, N. Vazquez-Laslop, A. S. Mankin, J. S. Fraser, D. Galonic Fujimori

This study determines cryo-EM structures of oxazolidinone antibiotics bound to stalled ribosomes, revealing how alanine at the penultimate position enables context-specific inhibition.

bioRxiv · Aug 10, 2021Biophysics

A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis

V. Jayaraman, D. J. Lee, N. Elad, S. Vimer, M. Sharon, J. S. Fraser, D. S. Tawfik

The paper identifies a counter-enzyme complex in Bacillus subtilis that regulates glutamate metabolism by inhibiting GudB activity, essential for growth under varying glutamate conditions.

bioRxiv · Apr 12, 2021Biochemistry

Contributions to human breast milk microbiome and enteromammary transfer of Bifidobacterium breve

K. Kordy, T. Gaufin, M. Mwangi, F. Li, C. Cerini, D. J. Lee, H. Adisetiyo, C. Woodward, P. S. Pannaraj, N. H. Tobin, G. M. Aldrovandi

The paper investigates the origin of breast milk microbes and identifies Bifidobacterium breve transmission via the enteromammary pathway in a C-section infant.

bioRxiv · Jul 1, 2019Microbiology