Author

D. J. McConkey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

H. Al-Ahmadie· 2 shared W. Choi· 2 shared A. D. Viny· 1 shared A. de Reynies· 1 shared A. G. Robertson· 1 shared A. Hartmann· 1 shared A. K. Aragaki· 1 shared A. Kamoun· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

H. Al-Ahmadie

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Author profile →

3 papers

Recent·Most cited

Combined Mek inhibition and Pparg activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis

T. Tate, S. A. Plumber, H. Al-Ahmadie, X. Chen, W. Choi, C. Lu, A. D. Viny, E. Batourina, K. Gretarsson, B. Alija, A. Molotkov, G. Wiessner, J. M. Mckiernan, D. J. McConkey, C. Dinney, , C. L. Mendelsohn

This study shows that combining MEK inhibition and Pparg activation eradicates muscle-invasive bladder cancer in a mouse model by reversing tumor differentiation and inducing apoptosis.

bioRxiv · Aug 19, 2023 · PreprintCancer Biology

The indoleamine 2,3 dioxygenase pathway drives intratumoral B cell maintenance.

B. A. Johnson, A. K. Aragaki, D. M. Williams, O. Rogers, J. Mountain, L. Luo, W. Zhang, L. Xian, M. Feng, L. Chia, D. Dordai, N. M. Hahn, S. Desiderio, T. S. Johnson, D. J. McConkey, L. M. S. Resar

This study shows that inhibiting the IDO1 pathway reduces tumor-infiltrating B cells in melanoma models, suggesting potential therapeutic strategies for solid tumors.

bioRxiv · Aug 25, 2021 · PreprintImmunology

A consensus molecular classification of muscle-invasive bladder cancer

A. Kamoun, A. de Reynies, Y. Allory, G. Sjodahl, A. G. Robertson, R. Seiler, K. Hoadley, H. Al-Ahmadie, W. Choi, C. S. Groeneveld, M. A. A. Castro, J. Fontugne, P. Eriksson, Q. Mo, J. Kardos, , The Bladder Cancer Molecular Taxonomy Group

The paper identifies six consensus molecular classes of muscle-invasive bladder cancer using transcriptomic data and classification systems, providing a framework for future biomarker validation.

bioRxiv · Apr 27, 2019Cancer Biology