D. Leach

An automated, high throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma

The paper optimizes an automated high-throughput method for isolating cell-free mitochondrial and nuclear DNA from plasma, achieving 6-fold higher yields of mitochondrial DNA.

Deletion of Sphingosine 1-Phosphate Receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

This study shows that deleting S1P1 in cardiomyocytes during development causes ventricular hypertrabeculation, fibrosis, and conduction abnormalities, despite preserved systolic function.