T. M. Nguyen

This paper develops a scalable, GMP-compatible cell therapy for Dystrophic Epidermolysis Bullosa using CRISPR-corrected iPS cells to generate functional skin grafts.

The paper isolates and characterizes myxobacteria from Vietnam, identifies their phylogeny, and evaluates their antioxidant and antimicrobial potential.

This study develops a platform to identify off-target degradation of ZF proteins by PROTACs and identifies design rules to reduce off-target effects using pomalidomide analogs.

This study identifies the futalosine pathway as a target for inhibiting Chlamydia trachomatis infection using docosahexaenoic acid and shows that menaquinone-7 is essential for its survival.

This study determines the crystal structures of DRH-3 domains bound to RNA, revealing structural features that explain its role in RNAi and evolutionary divergence from Dicer-like helicases.

This paper demonstrates that allowing microbial cells to switch phenotypes around a threshold, rather than enforcing a fixed trajectory, leads to more stable population behavior during continuous cultivation.

The paper identifies the long noncoding RNA LOUP as a mediator of RUNX1 and RUNX1-ETO effects in t(8;21) AML, showing it promotes myeloid differentiation and inhibits cell growth by regulating PU.1 expression.

This study compares the virulence of Cryptococcus neoformans ST5 and non-ST5 isolates in HIV-infected and uninfected patients in Vietnam, finding ST5 isolates show greater variability and initial inflammatory response but lower fungal burden in mice.

The paper introduces a method called segregostat to control phenotypic diversification in microbial populations by using glucose pulses based on real-time analysis of membrane permeability.