M. Salmeron-Sanchez

This study evaluates bioactive coatings on 3D printed PCL-TMA900 scaffolds for bone regeneration using a murine femur defect model, finding that Laponite/BMP-2 coating significantly promotes bone formation without heterotopic bone formation.

This study evaluates bioactive coatings on 3D-printed PCL-TMA scaffolds for bone regeneration, showing in vitro osteogenic response but no significant in vivo bone formation.

This study shows that 3D environments influence fibroblast inflammation in rheumatoid arthritis, with soft hydrogels promoting a resolving phenotype and stiff scaffolds restoring inflammatory profiles.

This study develops a bioengineered niche that maintains long-term haematopoietic stem cells by recreating physiological extracellular matrix organisation, supporting their survival and function without media supplementation.

The paper shows Collagen-VI is upregulated in pancreatic cancer cells on soft substrates and promotes metastasis by supporting the metastatic niche.

This study shows that nanovibrational stimulation of MSCs induces ROS and low-level inflammation, mimicking natural bone healing, and uses this to design a 3D bone tissue scaffold.

This paper identifies lithium as a Wnt agonist that stabilizes β-catenin and drives ESC differentiation into hemogenic endothelium and HSCs in vitro.

This study shows that topographically textured microparticles can enhance osteogenic markers in mesenchymal stem cells without exogenous factors.

This study shows boron enhances osteogenesis in MSCs by activating the BMP canonical pathway through NaBC1 interaction with BMPR1A and integrins, without using growth factors.

This study uses nanovibration to induce osteogenic differentiation in MSCs without exogenous growth factors, identifying cholesterol sulphate and fludrocortisone acetate as potent bioactive metabolites.

This study shows that fibronectin-coated biomaterials can rescue matrix and cellular defects in fibroblasts with collagen IV mutations.

This study develops fibronectin-based hydrogels that present growth factors to enhance angiogenesis and bone regeneration in vitro and in vivo.

This study shows nanotopography can control MSC immunomodulatory capacity by modulating intracellular tension and oxidative glycolysis, and identifies bioactive metabolites that influence MSC function.