Author

D. Orlova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Moussion· 2 shared A. Kosters· 1 shared A. Ritter· 1 shared A. Yang· 1 shared A. Zijlstra· 1 shared B. Nabet· 1 shared B. R. Babcock· 1 shared B. S. Dobosh· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

C. Moussion

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy

X. Li, J. Eastham, J. M. Giltnane, W. Zou, A. Zijlstra, E. Tabatsky, R. Banchereau, C.-W. Chang, B. Nabet, N. Patil, L. Molinero, S. Chui, M. Peterson, S. Lau, L. Rangell, , H. Koeppen

This paper develops automated tumor immunophenotyping pipelines to predict clinical benefit from anti-PD-L1 therapy in NSCLC and TNBC patients.

bioRxiv · Apr 3, 2023Pathology

Pathogenic neutrophilia drives acute respiratory distress syndrome in severe COVID-19 patients

D. J. Eddins, J. Yang, A. Kosters, V. Giacalone, X. Pechuan, J. D. Chandler, J. Eum, B. R. Babcock, B. S. Dobosh, M. R. Hernandez, F. Abdulkhader, G. L. Collins, R. P. Ramonell, C. Moussion, D. Orlova, , E. Ghosn

The paper identifies pathogenic neutrophilia as a driver of acute respiratory distress syndrome in severe COVID-19 patients, highlighting IL-8/CXCR2-mediated neutrophil recruitment and hyperinflammation.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Surveillance of in situ tumor arrays reveals early environmental control of cancer immunity

G. Ortiz-Munoz, M. Brown, C. B. Carbone, J. Pechuan Jorge, A. Ritter, D. Orlova, S. R. Mantri, A. Yang, J. Doerr, S. Mariathasan, Y. Wang, S. Turley, C. Gomez-Roca, C. Eduardo de Andrea, D. Spigel, , C. Moussion

This study introduces STAMP, a method to monitor tumor-immune dynamics in vivo, showing immune phenotypes evolve over time and correlate with therapeutic response.

bioRxiv · May 27, 2021 · PreprintCancer Biology