Cell BiologybioRxivPreprint
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway
I. Dulloo, M. Tellier, C. Levet…·M. Freeman
The paper identifies a novel ER-to-nucleus signaling pathway mediated by iRhom2 cleavage by the signal peptidase complex, linking it to psoriasis and TOC.
DOI 10.1101/2022.11.28.518246