Author

D. Roblyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

J. Ferruzzi· 2 shared J. J. Fredberg· 2 shared J. P. Butler· 2 shared M. H. Zaman· 2 shared A. F. Pegoraro· 1 shared C. A. Gomez· 1 shared C. Vergato· 1 shared C. Y. Park· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

J. Ferruzzi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A combined frequency domain near infrared spectroscopy and diffuse correlation spectroscopy system for comprehensive metabolic monitoring of inspiratory muscles during loading

C. A. Gomez, L. Brochard, E. Goligher, D. Rozenberg, W. D. Reid, D. Roblyer

This paper develops and validates a combined FD-NIRS and DCS system to monitor inspiratory muscle metabolism during loading, showing distinct dynamics in blood flow and oxygen metabolism compared to traditional parameters.

bioRxiv · Nov 30, 2023Bioengineering

Type-I interferon signaling is essential for robust metronomic chemo-immunogenic tumor regression in murine triple-negative breast cancer

C. Vergato, K. A. Doshi, D. Roblyer, D. J. Waxman

This study shows that type-I interferon signaling is essential for cyclophosphamide-induced tumor regression in mouse TNBC models through chemo-immunogenic mechanisms.

bioRxiv · Dec 5, 2021Cancer Biology

Epithelial layer unjamming shifts energy metabolism toward glycolysis

S. J. DeCamp, V. M. K. Tsuda, J. Ferruzzi, S. A. Koehler, D. Roblyer, J. T. Giblin, M. H. Zaman, S. T. Weiss, M. DeMarzio, C. Y. Park, N. C. Ogassavara, J. A. Mitchel, J. P. Butler, J. J. Fredberg

The paper shows that during epithelial layer unjamming, cells shift their metabolism toward glycolysis, even in regions without visible morphological changes.

bioRxiv · Jun 30, 2020Biophysics

Tumor invasion as non-equilibrium phase separation

W. Kang, J. Ferruzzi, C.-P. Spatarelu, Y. L. Han, Y. Sharma, S. Koehler, J. P. Butler, D. Roblyer, M. H. Zaman, M. Guo, Z. Chen, A. F. Pegoraro, J. J. Fredberg

The paper shows tumor spheroids exhibit solid-like, fluid-like, and gas-like phases during invasion, with phase transitions influenced by cell type and matrix density.

bioRxiv · Apr 28, 2020 · PreprintBiophysics