Author

Y. L. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Guo· 3 shared J. J. Fredberg· 2 shared A. F. Pegoraro· 1 shared A. Vahabikashi· 1 shared C. Tang· 1 shared C. Y. Park· 1 shared C.-P. Spatarelu· 1 shared D. Roblyer· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

M. Guo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Recovery of structural integrity of epithelial monolayer in response to massive apoptosis-induced defects

Y. Yuan, Y. L. Han, J. Xia, H. Li, C. Tang, F. Ye, D. Weitz, M. Guo

This study shows that epithelial monolayers recover structural integrity after apoptosis-induced defects through enhanced cell spreading, migration, and traction forces.

bioRxiv · Aug 8, 2022 · PreprintBiophysics

Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole cell mechanics

A. Vahabikashi, S. Sivagurunathan, F. A. S. Nicdao, Y. L. Han, C. Y. Park, X. Wong, J. R. Tran, G. G. Gundersen, K. Reddy, G. G. Luxton, M. Guo, J. J. Fredberg, Y. Zheng, S. A. Adam, R. D. Goldman

This study shows that different nuclear lamin isoforms modulate cell and nuclear mechanics by affecting LINC complex stability and heterochromatin structure in mouse embryonic fibroblasts.

bioRxiv · May 12, 2021Biophysics

Tumor invasion as non-equilibrium phase separation

W. Kang, J. Ferruzzi, C.-P. Spatarelu, Y. L. Han, Y. Sharma, S. Koehler, J. P. Butler, D. Roblyer, M. H. Zaman, M. Guo, Z. Chen, A. F. Pegoraro, J. J. Fredberg

The paper shows tumor spheroids exhibit solid-like, fluid-like, and gas-like phases during invasion, with phase transitions influenced by cell type and matrix density.

bioRxiv · Apr 28, 2020 · PreprintBiophysics