Author

D. T. Long

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Amalric· 1 shared A. Blackman· 1 shared A. C. Rees· 1 shared A. Chatoff· 1 shared A. J. Emanuel· 1 shared A. R. Cole· 1 shared A. Uboveja· 1 shared B. G. Bitler· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Amalric

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2 papers

Recent·Most cited

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

A. Uboveja, Z. Huang, R. Buj, A. Amalric, H. Wang, N. K. Tangudu, A. R. Cole, E. Megill, D. Kantner, A. Chatoff, H. Ahmad, M. M. Marcinkiewicz, J. A. Disharoon, S. Graff, E. S. Dahl, , K. M. Aird

This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.

bioRxiv · Feb 6, 2024Cancer Biology

MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model

A. Blackman, A. C. Rees, R. R. Bowers, C. M. Jones, S. G. Vaena, M. A. Clark, S. Carter, E. Villamor, D. Evans, A. J. Emanuel, G. Fullbright, D. T. Long, L. Spruill, M. J. Romeo, K. L. Helke, J. R. Delaney

This paper shows that combining MYC and p53-R270H mutations in a mouse model generates high-grade serous ovarian and uterine serous carcinomas with human-like genetic and transcriptomic features.

bioRxiv · Jan 24, 2024Cancer Biology