MicrobiologyNature CommunicationsPeer-reviewed
Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium
A. M. Hogan, A. Natarajan, D. T. Maydaniuk…·S. T. Cardona
This study identifies cell envelope-associated resistance and susceptibility determinants in Burkholderia cenocepacia using transposon mutagenesis and antibiotic profiling, revealing new vulnerabilities to β-lactams and the mechanism of cefiderocol.
DOI 10.1038/s41467-023-40494-5