Author

S. T. Cardona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. M. Hogan· 3 shared A. Bosch· 1 shared A. Motnenko· 1 shared A. Natarajan· 1 shared A. S. M. Z. Rahman· 1 shared B. Leon· 1 shared B. Wu· 1 shared C. Ras· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

A. M. Hogan

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4 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedAug 9, 2023

Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium

A. M. Hogan, A. Natarajan, D. T. Maydaniuk…·S. T. Cardona

This study identifies cell envelope-associated resistance and susceptibility determinants in Burkholderia cenocepacia using transposon mutagenesis and antibiotic profiling, revealing new vulnerabilities to β-lactams and the mechanism of cefiderocol.

DOI 10.1038/s41467-023-40494-5

bacteria (other)whole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivSep 10, 2021

New auranofin analogs with antibacterial properties against Burkholderia clinical isolates

D. Maydaniuk, B. Wu, D. Truong…·S. T. Cardona

This study identifies two auranofin analogs, MS-40S and MS-40, with antibacterial activity against Burkholderia clinical isolates, including B. cenocepacia, and low toxicity in model organisms.

DOI 10.3390/antibiotics10121443

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivSep 25, 2019

Phenylacetyl-CoA, not phenylacetic acid, attenuates CepIR-regulated virulence in Burkholderia 2 cenocepacia

T. J. Lightly, K. L. Frejuk, M.-C. Groleau…·S. T. Cardona

The paper shows that phenylacetyl-CoA, not phenylacetic acid, suppresses virulence in Burkholderia cenocepacia by indirectly affecting CepIR-regulated pathways.

DOI 10.1128/aem.01594-19

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologyACS Synthetic BiologyPeer-reviewedSep 6, 2019

A broad-host-range CRISPRi toolkit for silencing gene expression in Burkholderia

A. M. Hogan, A. S. M. Z. Rahman, T. L. Lightly, S. T. Cardona

This paper develops a broad-host-range CRISPRi toolkit for gene silencing in Burkholderia species, demonstrating its utility in studying gene function and pathogenicity.

DOI 10.1021/acssynbio.9b00232

genetic perturbation / CRISPRgene regulatory network inference

𝕏 PostBluesky