D. Walsh

A new model of endotracheal tube biofilm identifies combinations of matrix-degrading enzymes and antimicrobials able to eradicate biofilms of pathogens that cause ventilator-associated pneumonia

This paper introduces an in vitro model of endotracheal tube biofilms that demonstrates the effectiveness of combining matrix-degrading enzymes with antimicrobials to eradicate pathogens causing ventilator-associated pneumonia.

Shear stress-induced restoration of pulmonary endothelial barrier function following ischaemia reperfusion injury requires VEGFR2 signalling

This study shows that shear stress helps restore endothelial barrier function after ischaemia reperfusion injury, and this process requires VEGFR2 signaling but not VEGFA binding.

Anti-prion drugs do not improve survival in knock-in models of inherited prion disease

This study tests anti-prion drugs on knock-in mouse models of inherited prion diseases and finds they do not improve survival or prevent prion accumulation.

The biocide triclosan induces (p)ppGpp dependent antibiotic tolerance and alters SarA dependent biofilm structures in Staphylococcus aureus

Detection of bifenthrin, bifenazate, etoxazole resistance in Tetranychus urticae collected from mint fields and hop yards using targeted sequencing and TaqMan approaches

The paper uses TaqMan qPCR and targeted sequencing to detect miticide resistance mutations in Tetranychus urticae from mint and hop fields, showing the method's accuracy but highlighting challenges in mixed populations.

Multiplex PCR reveals unique trends in pathogen and parasitoid infestations of alfalfa leafcutting brood cells.

The study uses multiplex PCR to identify pathogens and parasitoids in alfalfa leafcutting bee brood cells, revealing co-infections and new species.

Examining historical rates of leafcutting bee cell pathogens to establish baseline infectivity rates for alfalfa seed growers

The paper analyzes historical infection rates of pathogens and parasitoids in alfalfa leafcutting bee cells to establish baseline infectivity rates for managing bee health.

The biomedical sensor Cell-Fit-HD4D, reveals individual tumor cell fate in response to microscopic ion deposition.

The paper introduces a biomedical sensor, Cell-Fit-HD4D, to monitor individual tumor cell fate after ion beam therapy and demonstrates its ability to visualize ion beams and track cell responses.

Diversity and biogeography of SAR11 bacteria from the Arctic Ocean

The paper investigates SAR11 bacterial diversity in the Arctic Ocean, identifying distinct ecotypes and their association with water masses and depth.

Microbial life under ice: metagenome diversity and in situ activity of Verrucomicrobia in seasonally ice-covered lakes

This study examines Verrucomicrobia diversity and metabolic activity under ice in northern lakes using metagenomics and metatranscriptomics, revealing their active role in ice-covered environments.

Genomic evidence for the degradation of terrestrial organic matter by pelagic Arctic Ocean Chloroflexi bacteria

The paper identifies aromatic compound degradation genes in Arctic Ocean Chloroflexi bacteria, suggesting they can utilize terrestrial organic matter and may play a growing role in the carbon cycle.