D. Yeo

Tissue Tension and Strain as Indicators of Suction-mediated Cutaneous DNA Transfection: A Parametric Study

The paper evaluates cutaneous suction transfection efficacy using GFP expression in rats, identifying strain and tension as indicators for optimizing transfection protocols.

An integrative taxonomic treatment of the Mycetophilidae (Diptera: Bibionomorpha) from Singapore reveals 115 new species on 730km2

The paper describes 115 new species of fungus gnats from Singapore using molecular and morphological data, highlighting the taxonomic challenges in species-rich clades.

"Dark taxonomy": a new protocol for overcoming the taxonomic impediments for dark taxa and broadening the taxon base for biodiversity assessment

This paper introduces 'dark taxonomy' to address taxonomic impediments by using small-scale revisions and integrative methods, increasing described species in the Oriental region by 25%.

Global convergence of dominance and neglect in flying insect diversity

The paper analyzes global flying insect diversity using DNA sequencing from Malaise traps, finding 20 families dominate species diversity worldwide despite high species turnover and taxonomic neglect.

A re-analysis of the data in Sharkey et al.'s (2021) minimalist revision reveals that BINs do not deserve names, but BOLD Systems needs a stronger commitment to open science

This paper re-analyzes BINs from Sharkey et al. (2021) and finds they are unstable and insufficiently described, highlighting issues with BOLD Systems' use of proprietary data and algorithms.

MinION barcodes: biodiversity discovery and identification by everyone, for everyone

This paper introduces a low-cost, accessible workflow and software for DNA barcoding using MinION sequencing, achieving high accuracy comparable to Sanger and Illumina methods.

Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates

This paper develops tandem-cleavage linkers to improve ADC stability and tolerability, showing better hematopoietic safety in rat studies.

Mangroves are an overlooked hotspot of insect diversity despite low plant diversity

The paper compares insect diversity across different forest types and finds that mangroves, despite low plant diversity, host a rich and distinct insect fauna.

A novel HER2-targeted antibody-drug conjugate offers the possibility of clinical dosing at trastuzumab-equivalent exposure levels

This paper develops a novel HER2-targeted ADC, CAT-01-106, showing improved efficacy and tolerability compared to T-DM1 at equivalent payload dosing.

Longer is not always better: Optimizing barcode length for large-scale species discovery and identification

This study compares full-length and mini-barcodes for species identification using empirical and GenBank datasets, finding no significant performance difference for mini-barcodes over 200-bp.