Author

M. Bauzon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:rat· 2 Organism:human· 1 Assay:imaging· 1 Assay:protein structure· 1

Frequent Co-Authors

A. O. Ogunkoya· 2 shared C. Hickle· 2 shared D. Rabuka· 2 shared D. Yeo· 2 shared F. Zhang· 2 shared M. Kanada· 2 shared P. M. Drake· 2 shared R. M. Barfield· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. O. Ogunkoya

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Phosphatidylserine-exposing medium/large extracellular vesicles: potential cancer biomarkers

G. I. Perez, M. P. Bernard, D. Vocelle, A. A. Zarea, D. Schneider, M. Bauzon, T. Hermiston, M. Kanada

This study identifies medium/large extracellular vesicles (m/lEVs) exposing phosphatidylserine (PS) as potential cancer biomarkers, showing higher PS externalization in cancer-derived m/lEVs compared to non-cancerous ones.

bioRxiv · Nov 17, 2022 · PreprintCancer Biology

Gla-domain mediated targeting of externalized phosphatidylserine for intracellular delivery

T. Hermiston, J. Hardy, M. Bauzon, F. G. Blankenberg, M. Kanada, A. Makela, C. K. F. Chan, C. H. Contag

This paper describes a GLA-domain that binds externalized phosphatidylserine and enables rapid, energy-independent intracellular delivery of probes in animal models.

bioRxiv · Jun 13, 2022Cell Biology

Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates

S. Chuprakov, A. O. Ogunkoya, R. M. Barfield, M. Bauzon, C. Hickle, Y. C. Kim, D. Yeo, F. Zhang, D. Rabuka, P. M. Drake

This paper develops tandem-cleavage linkers to improve ADC stability and tolerability, showing better hematopoietic safety in rat studies.

bioRxiv · Jan 19, 2021Pharmacology & Toxicology

A novel HER2-targeted antibody-drug conjugate offers the possibility of clinical dosing at trastuzumab-equivalent exposure levels

R. M. Barfield, Y. C. Kim, S. Chuprakov, F. Zhang, M. Bauzon, A. O. Ogunkoya, D. Yeo, C. Hickle, M. D. Pegram, D. Rabuka, P. M. Drake

This paper develops a novel HER2-targeted ADC, CAT-01-106, showing improved efficacy and tolerability compared to T-DM1 at equivalent payload dosing.

bioRxiv · Mar 13, 2020Pharmacology & Toxicology