Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.
Brooke K. Hayes, Marina Harper, Hariprasad Venugopal…·Sheena McGowan
The paper presents the structure of Tse15, a T6SS Rhs effector from Acinetobacter baumannii, revealing a novel mechanism for toxin delivery and activation involving auto-cleavage and domain interaction.