Author

E. A. Singer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. M. Ulrich· 3 shared M. L. Churchman· 3 shared A. A. Tarhini· 2 shared A. C. Tan· 2 shared A. E. G. Osman· 2 shared A. P. Ikeguchi· 2 shared C. E. Wheeler· 2 shared D. Spakowicz· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

C. M. Ulrich

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer

M. Benej, R. Hoyd, M. Kreamer, C. E. Wheeler, D. J. Grencewicz, F. Choueiry, C. H. Chan, Y. Zakharia, Q. Ma, R. D. Dodd, C. M. Ulrich, S. Hardikar, M. L. Churchman, A. A. Tarhini, L. A. Robinson, , D. Spakowicz

The paper examines how hypoxia affects the tumor microbiome and its interaction with radiation response in colorectal cancer using RNA-seq data and experimental models.

bioRxiv · Sep 1, 2023Immunology

Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content

V. Guerrini, B. Prideaux, R. Khan, S. Subbian, Y. Wang, E. Sadimin, S. Pawar, R. Ukey, E. A. Singer, C. Xue, M. L. Gennaro

The paper investigates lipid accumulation in foam cells across different diseases and finds that lipid content varies by disease and microenvironment.

bioRxiv · Jun 8, 2023Immunology

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors

C. E. Wheeler, , S. S. Coleman, R. Hoyd, L. Denko, C. H. F. Chan, M. L. Churchman, N. Denko, R. D. Dodd, I. Eljilany, S. Hardikar, M. Husain, A. P. Ikeguchi, N. Jin, Q. Ma, M. D. McCarter, , A. C. Tan

This study identifies microbes associated with immunotherapy response in metastatic melanoma and shows that combining microbe abundances with gene expression improves survival prediction.

bioRxiv · May 24, 2023 · PreprintImmunology

Replicative Instability Drives Cancer Progression

B. B. Morris, J. P. Smith, Q. Zhang, Z. Jiang, O. A. Hampton, M. L. Churchman, S. M. Arnold, D. H. Owen, J. E. Gray, P. M. Dillon, H. H. Soliman, D. G. Stover, H. Colman, A. Chakravarti, K. H. Shain, , M. W. Mayo

This study identifies a pan-cancer class of tumors driven by replicative instability, showing it accelerates cancer progression through genomic changes and transcriptional rewiring.

bioRxiv · May 6, 2022Cancer Biology