Author

M. Husain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. A. Tarhini· 2 shared A. C. Tan· 2 shared A. E. G. Osman· 2 shared A. P. Ikeguchi· 2 shared C. E. Wheeler· 2 shared C. M. Ulrich· 2 shared D. Spakowicz· 2 shared E. A. Singer· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. A. Tarhini

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters

S. Khan, M. Chakraborty, F. Wu, N. Chen, T. Wang, Y. T. Chan, A. Sayad, J.-D. S. Vasquez, M. Kotlyar, K. Nguyen, Y. Huang, F. J. Alibhai, M. Woo, R.-K. Li, M. Husain, , D. A. Winer

The paper identifies B cells as drivers of T cell immunosenescence and aging, showing that targeting B cells with CD20 antibodies can reverse age-related T cell dysfunction.

bioRxiv · Sep 12, 2023 · PreprintImmunology

The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer

M. Benej, R. Hoyd, M. Kreamer, C. E. Wheeler, D. J. Grencewicz, F. Choueiry, C. H. Chan, Y. Zakharia, Q. Ma, R. D. Dodd, C. M. Ulrich, S. Hardikar, M. L. Churchman, A. A. Tarhini, L. A. Robinson, , D. Spakowicz

The paper examines how hypoxia affects the tumor microbiome and its interaction with radiation response in colorectal cancer using RNA-seq data and experimental models.

bioRxiv · Sep 1, 2023Immunology

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors

C. E. Wheeler, , S. S. Coleman, R. Hoyd, L. Denko, C. H. F. Chan, M. L. Churchman, N. Denko, R. D. Dodd, I. Eljilany, S. Hardikar, M. Husain, A. P. Ikeguchi, N. Jin, Q. Ma, M. D. McCarter, , A. C. Tan

This study identifies microbes associated with immunotherapy response in metastatic melanoma and shows that combining microbe abundances with gene expression improves survival prediction.

bioRxiv · May 24, 2023 · PreprintImmunology

Long-term functional culture and in vitro manipulation of adult mouse cardiomyocytes

N. I. Callaghan, S.-H. Lee, S. Hadipour-Lakmehsari, X. A. Lee, M. A. Siraj, A. Driouchi, C. M. Yip, M. Husain, C. A. Simmons, A. O. Gramolini

This study develops methods to culture adult mouse cardiomyocytes long-term, maintaining their structure and function for in vitro experiments and genetic manipulations.

Communications Biology · May 11, 2020Peer-reviewedCell Biology

Type I interferons are important co-stimulatory signals during T cell receptor mediated MAIT cell activation

R. Lamichhane, H. Galvin, R. F. Hannaway, S. M. de la Harpe, F. Munro, J. D. Tyndall, A. J. Vernall, J. L. McCall, M. Husain, J. E. Ussher

This study shows that type I interferons enhance TCR-mediated MAIT cell activation by boosting cytokine and granzyme B production.

bioRxiv · Jul 2, 2019Immunology

Transcranial photobiomodulation with infrared laser increases power of brain oscillations

X. Wang, J. Dmochowski, L. Zeng, E. Kallioniemi, M. Husain, F. Gonzalez-Lima, H. Liu

This study shows that transcranial photobiomodulation with a 1064-nm laser increases alpha and beta band EEG power in the human brain during resting conditions.

bioRxiv · Jan 31, 2019 · PreprintBioengineering