N. Jin

Development of alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell derived liver organoids

This study develops a human induced pluripotent stem cell-derived liver organoid model of alcoholic liver disease to evaluate drug treatments and replicate key pathological features.

The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer

The paper examines how hypoxia affects the tumor microbiome and its interaction with radiation response in colorectal cancer using RNA-seq data and experimental models.

Presence of the ER-Golgi intermediate compartment that matures into the Golgi in yeast

The paper identifies and characterizes the ER-Golgi intermediate compartment in yeast using live-cell imaging, showing its maturation into the Golgi.

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors

This study identifies microbes associated with immunotherapy response in metastatic melanoma and shows that combining microbe abundances with gene expression improves survival prediction.

Fertilizer reduction with bio-organic fertilizer to regulate the root soil microbial community structure to improve Baby Chinese cabbage yield

This study investigates how reducing chemical fertilizers and adding bio-organic fertilizer affects soil microbial communities and Baby Chinese cabbage yield in Gansu plateau, finding that T2 treatment yields the highest crop output.

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

This study shows that a proinsulin mutation increases susceptibility to diet-induced diabetes in mice, with severity linked to genetic dosage and beta-cell dysfunction.

Acute and chronic toxicity assessment of benzylpenicillin G residues in heat-treated animal food products

This study assesses the acute and chronic toxicity of benzylpenicillin G residues in heat-treated animal food products using a mouse model, finding reduced LD50 and organ damage at high exposure levels.