Author

E. Abby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Gerstung· 2 shared S. H. Ong· 2 shared A. Herms· 1 shared A. Kalogeropoulou· 1 shared A. R. Lowe· 1 shared B. A. Hall· 1 shared B. Colom· 1 shared C. King· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

M. Gerstung

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Author profile →

2 papers

Recent·Most cited

Epithelioids: Self-sustaining 3D epithelial cultures to study long-term processes

A. Herms, D. Fernandez-Antoran, M. Alcolea, A. Kalogeropoulou, U. Banerjee, G. Piedrafita, E. Abby, J. A. Valverde-Lopez, I. S. Ferreira, S. Dentro, S. H. Ong, B. Colom, K. Murai, C. King, K. T. Mahbubani, , P. H. Jones

This paper introduces epithelioids, a 3D culture system for mouse and human epithelia that maintains structure and function over long periods, enabling study of long-term biological processes.

bioRxiv · Jan 3, 2023Cell Biology

Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

E. Abby, S. C. Dentro, M. W. J. Hall, J. C. Fowler, S. H. Ong, R. Sood, C. W. Siebel, M. Gerstung, B. A. Hall, P. Jones

The paper shows NOTCH1 mutations promote clonal expansion in normal esophageal epithelium but hinder tumor growth, suggesting NOTCH1 inhibition could prevent esophageal squamous cancer.

bioRxiv · Jun 18, 2021 · PreprintCancer Biology