Author

C. King

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2 Cell Biology· 2 Biophysics· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:human· 6 Organism:mouse· 4 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

A. Herms· 2 shared B. Colom· 2 shared D. Fernandez-Antoran· 2 shared K. Saeb-Parsy· 2 shared M. Alcolea· 2 shared M. Gerstung· 2 shared S. Dentro· 2 shared S. H. Ong· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

A. Herms

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Author profile →

10 papers

Recent·Most cited

Multiple Unfolded Protein Response pathways cooperate to link cytosolic dsDNA release to Stimulator of Interferon Gene (STING) activation

T. Hu, Y. Liu, J. Fleck, C. King, E. Schalk, Z. Zhang, A. Mehle, J. A. Smith

This study identifies multiple UPR pathways that cooperate to link cytosolic dsDNA release to STING activation and IFN-β induction in response to ER stress.

bioRxiv · May 10, 2024Immunology

ASPYRE-Lung: Validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in tissue

R. T. Evans, E. Gillon-Zhang, J. N. Brown, K. E. Knudsen, C. King, A. S. Green, A.-L. Silva, J. M. Mordaka, R. N. Palmer, A. Tomassini, A. Collazos, C. Xyrafaki, I. Turner, C. H. Ho, D. Nugent, , R. J. Osborne

The paper validates ASPYRE-Lung, a method for detecting actionable variants in NSCLC tissue with high sensitivity, specificity, and precision.

bioRxiv · Feb 7, 2024Cancer Biology

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes

J. Nixon-Abell, F. S. Ruggeri, S. Qamar, T. W. Herling, M. A. Czekalska, Y. Shen, G. Wang, C. King, M. S. Fernandopulle, T. Sneideris, J. L. Watson, V. V. Pillai, W. Meadows, J. Henderson, J. E. Chambers, , P. St George Hyslop

This study shows ANXA11 biomolecular condensates couple protein and lipid phase states on lysosomal membranes through interactions with ALG2 and CALC.

bioRxiv · Mar 22, 2023Cell Biology

Epithelioids: Self-sustaining 3D epithelial cultures to study long-term processes

A. Herms, D. Fernandez-Antoran, M. Alcolea, A. Kalogeropoulou, U. Banerjee, G. Piedrafita, E. Abby, J. A. Valverde-Lopez, I. S. Ferreira, S. Dentro, S. H. Ong, B. Colom, K. Murai, C. King, K. T. Mahbubani, , P. H. Jones

This paper introduces epithelioids, a 3D culture system for mouse and human epithelia that maintains structure and function over long periods, enabling study of long-term biological processes.

bioRxiv · Jan 3, 2023Cell Biology

A dynamic epibiont community associated with the bone eating worm Osedax

S. Goffredi, B. Panossian, C. Brzechffa, N. Field, C. King, G. Moggioli, G. W. Rouse, J. M. Martin-Duran, L. Henry

The paper identifies a dynamic epibiont community of Campylobacterales on Osedax worms that shift over time as whale carcasses decompose, showing metabolic transitions and genetic features suggesting long-term host interactions.

bioRxiv · Nov 14, 2022 · PreprintMicrobiology

Precancer: Mutant clones in normal epithelium outcompete and eliminate esophageal micro-tumors

B. Colom, A. Herms, S. Dentro, C. King, R. Sood, M. Alcolea, D. Fernandez-Antoran, S. H. Ong, J. C. Fowler, K. Mahbubani, K. Saeb-Parsy, M. Gerstung, B. A. Hall, P. Jones

The paper shows that mutant clones in normal epithelium outcompete and eliminate esophageal micro-tumors through cell competition, preventing tumor formation.

bioRxiv · Jun 25, 2021Cancer Biology

A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against P. vivax antigens in a multiplexed bead-based assay using Luminex(R) technology (Bio-Plex(R)200 or MAGPIX(R))

R. Mazhari, J. Brewster, R. Fong, C. Bourke, Z. S. Liu, E. Takashima, T. Tsuboi, W.-H. Tham, M. Harbers, C. Chitnis, J. Healer, M. Ome-Kaius, J. Sattabongkot, J. Kazura, L. Robinson, , R. Longley

This study compares non-magnetic and magnetic beads for measuring IgG antibodies against P. vivax antigens using Luminex technology across different instruments, finding strong correlations but noting higher protein requirements for magnetic beads.

bioRxiv · Aug 10, 2020Immunology

Nepenthes maximoides (Nepenthaceae) a new, Critically Endangered (Possibly Extinct) species in Sect. Alatae from Luzon, Philippines showing striking pitcher convergence with N. maxima (Sect. Regiae) of Indonesia.

M. Cheek, C. King

The paper describes a new, Critically Endangered Nepenthes species from Luzon, Philippines, showing convergent evolution with an Indonesian species.

bioRxiv · Jun 27, 2020Plant Biology

ER membranes exhibit phase behavior at sites of organelle contact

C. King, P. Sengupta, A. Seo, J. Lippincott-Schwartz

The paper demonstrates that ER membranes can phase separate into liquid-ordered and liquid-disordered domains using Large Intra-Cellular Vesicles generated by hypotonic treatment.

bioRxiv · Jul 19, 2019Biophysics

Phospho-tuning immunity through Denisovan, modern human, and mouse TNFAIP3 gene variants

N. W. Zammit, O. M. Siggs, P. Gray, K. Horikawa, S. R. Daley, D. B. Langley, D. Cultrone, E. K. Malle, S. N. Walters, J. E. Villanueva, J. Warren, A. Russell, M. J. Cowley, V. Gayevskiy, M. E. Dinger, , M. E. Craig

The paper identifies TNFAIP3 variants in humans, Denisovans, and mice that modulate A20 phosphorylation, revealing a genetic mechanism for balancing immunity and microbial tolerance.

bioRxiv · Mar 27, 2019 · PreprintImmunology