Author

E. Andres-Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

L. C. Terron-Camero· 2 shared A. Arutyunyan· 1 shared A. Barroso· 1 shared A. Delgado· 1 shared A. M. Carcaboso· 1 shared A. M. Espinosa-Oliva· 1 shared A. Santos· 1 shared B. Benitez-Dominguez· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

L. C. Terron-Camero

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multi-omics framework to reveal the molecular determinants of fermentation performance in wine yeast populations

M. de Celis, J. Ruiz, B. Benitez-Dominguez, J. Vicente, S. Tomasi, S. Izquierdo-Gea, N. Rozes, C. Ruiz-de-Vila, J. Gombau, F. Zamora, A. Barroso, L. C. Terron-Camero, E. Andres-Leon, A. Santos, I. Belda

The paper develops a multi-omics framework to identify molecular factors influencing fermentation performance in wine yeast communities, finding that yeast dominance drives metabolite profiles and transcriptomic activity.

bioRxiv · Dec 2, 2023Microbiology

Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses

J. Rodriguez-Ubreva, A. Arutyunyan, M. J. Bonder, L. Del Pino-Molina, S. Clark, C. de la Calle-Fabregat, L. Garcia-Alonso, L.-F. Handfield, L. Ciudad, E. Andres-Leon, F. Krueger, F. Catala-Moll, V. C. Rodriguez-Cortez, K. Polanski, L. Mamanova, , E. Ballestar

The paper creates a single-cell atlas of CVID, identifying epigenetic and transcriptional defects in memory B cells and linking them to impaired cell communication.

bioRxiv · Dec 20, 2021 · PreprintImmunology

HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

D. J. Garcia-Dominguez, N. Hajji, S. Sanchez-Molina, E. Figuerola, R. M. de Pablos, A. M. Espinosa-Oliva, E. Andres-Leon, L. C. Terron-Camero, R. Flores-Campos, G. Pascual-Pasto, M. J. Robles, A. M. Carcaboso, J. Mora, E. de Alava, L. Hontecillas-Prieto

This study shows HDAC6 regulates EWSR1-FLI1 expression in Ewing sarcoma by modulating SP1 acetylation and promoter binding, with HDAC6 inhibition reducing oncogenic activity and enhancing treatment response.

bioRxiv · Jan 4, 2021Cancer Biology

Evidence for a role of phenotypic mutations in virus adaptation

R. Luzon-Hidalgo, V. A. Risso, A. Delgado, E. Andres-Leon, B. Ibarra-Molero, J. M. Sanchez-Ruiz

This study shows that virus adaptation can occur through phenotypic mutations rather than genetic mutations in the viral DNA polymerase.

bioRxiv · Aug 21, 2020Evolutionary Biology