A. Santos

Community successional patterns and inter-kingdom interactions during granular biofilm development

This study tracks microbial community succession and inter-kingdom interactions during granular biofilm development in a sequencing batch reactor over 343 days.

Multi-omics framework to reveal the molecular determinants of fermentation performance in wine yeast populations

The paper develops a multi-omics framework to identify molecular factors influencing fermentation performance in wine yeast communities, finding that yeast dominance drives metabolite profiles and transcriptomic activity.

Predictability of the community-function landscape in wine yeast ecosystems

The paper predicts community function in wine yeast ecosystems by linking taxonomy to enological traits and showing quantitative rules govern strain contributions to fermentation.

Regional pulmonary perfusion, blood volume, and their relationship change during early ARDS in an experimental study

This study examines how regional pulmonary perfusion and blood volume change in early ARDS using PET imaging in sheep, finding a shift from linear to curvilinear relationship between the two.

HMGB1 acts as an agent of host defense at the gut mucosal barrier

This study identifies HMGB1 as a host defense molecule in the gut mucosal barrier that targets bacterial adhesins to prevent microbial invasion and adhesion.

Multilocus typing of Lachancea thermotolerans for wine fermentation monitoring

This paper develops a multiplexed microsatellite amplification method for genotyping Lachancea thermotolerans strains to monitor fermentation and strain implantation in winemaking.

The Brazilian population of Fusarium oxysporum f. sp. cubense is not structured by VCG or by geographic origin

The study analyzes the genetic structure of Fusarium oxysporum f. sp. cubense in Brazil and finds no genetic structure based on VCG or geographic origin.

A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

The paper examines soil macroinvertebrate communities in Amazonian Dark Earths (ADEs) and finds higher biodiversity and biological activity compared to adjacent soils, highlighting the impact of human activities on Amazonian ecosystems.

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin

The paper creates a spatially and cell-type resolved proteomic atlas of healthy human skin, quantifying 10,701 proteins across different locations and cell types.

A paired liver biopsy and plasma proteomics study reveals circulating biomarkers for alcohol-related liver disease

This study identifies circulating proteomic biomarkers for alcohol-related liver disease using paired liver biopsy and plasma proteomics, showing improved performance over existing tests.

New insights into the paradoxical distribution of IRC7 in Saccharomyces cerevisiae and its associated phenotypic and genomic landscapes

The paper investigates the paradoxical distribution of the IRC7S allele in wine yeast strains and its phenotypic and genomic implications.

Characterization of the oral microbiome of medically controlled type-2 diabetes patients

This study characterizes the oral microbiome of type-2 diabetes patients in Portugal and finds no significant differences between patients and controls, though some taxa are more frequent in controls.

Detection of hypermucoviscous Klebsiella pneumoniae sequence type 86 capsular type K2 in South America as an unexpected cause of a fatal outbreak in captivity marmosets

The paper identifies hypermucoviscous K. pneumoniae ST86 K2 as the cause of a fatal marmoset outbreak in Brazil, highlighting its zoonotic potential and public health implications.

Integrative analysis of transcriptomic and clinical data uncovers the tumor suppressive activity of MITF in prostate cancer.

The paper identifies MITF as a tumor suppressor in prostate cancer and reveals CRYAB as a direct target mediating its suppressive activity through integrative transcriptomic and clinical analysis.

Interfering with MIF-CD74 signalling on macrophages and dendritic cells with a peptide-based approach restores the immune response against metastatic melanoma.

This study shows that a peptide-based therapy targeting the MIF-CD74 pathway in macrophages and dendritic cells can restore anti-tumour immunity in metastatic melanoma.

Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer.

This study shows that blocking insulin-like growth factors enhances paclitaxel's effectiveness against metastatic breast cancer by reducing tumor growth and lung metastasis in pre-clinical models.