In Vitro Efficacy of Next Generation Dihydrotriazines and Biguanides Against Babesiosis and Malaria Parasites
P. Vydyam, M. Chand, S. Gihaz, I. Renard, G. D. Heffernan, L. R. Jacobus, D. P. Jacobus, K. W. Saionz, R. Shah, H.-M. Shieh, J. Terpinski, W. Zhao, E. Cornillot, C. Ben Mamoun
This study screens dihydrotriazines and biguanides against Babesia and Plasmodium parasites to identify effective antifolates with broad-spectrum activity and high therapeutic indices.
bioRxiv · Mar 20, 2024Microbiology