Author

E. Dann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 5 Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Assay:spatial transcriptomics· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

K. Polanski· 5 shared C. Suo· 4 shared M. R. Clatworthy· 4 shared E. Stephenson· 3 shared J. C. Marioni· 3 shared J. Engelbert· 3 shared K. B. Meyer· 3 shared M. Haniffa· 3 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

K. Polanski

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Author profile →

6 papers

Recent·Most cited

Molecular control of the lymphocyte death timer

M. Ruhle, E. Thomas, E. Dann, N. Gottscheber, C. E. Teh, D. H. Gray, M. R. Dowling, S. Heinzel, P. D. Hodgkin

The paper identifies a protein-threshold mechanism that predicts lymphocyte death timing and shows how it integrates signals and is heritable across generations.

bioRxiv · Oct 25, 2023 · PreprintImmunology

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Early human lung immune cell development and its role in epithelial cell fate

J. L. Barnes, P. He, M. Yoshida, K. B. Worlock, R. G. H. Lindeboom, C. Suo, J. P. Pett, A. Wilbrey-Clark, E. Dann, L. Mamanova, L. Richardson, A. J. Oliver, A. L. Pennycuick, J. Allen-Hyttinen, I. T. Herczeg, , M. Z. Nikolic

The paper profiles lung immune cells during development using scRNAseq and identifies IL-1β's role in driving epithelial progenitor differentiation.

bioRxiv · Dec 13, 2022Immunology

Dandelion utilizes single cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

C. Suo, K. Polanski, E. Dann, R. G. H. Lindeboom, R. Vilarrasa Blasi, R. Vento-Tormo, M. Haniffa, K. B. Meyer, L. M. Dratva, Z. K. Tuong, M. R. Clatworthy, S. Teichmann

Dandelion improves V(D)J analysis in scVDJ-seq data, enabling better lineage commitment predictions and insights into lymphocyte development.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Mapping the developing human immune system across organs

C. Suo, E. Dann, I. Goh, L. Jardine, V. Kleshchevnikov, J.-E. Park, R. A. Botting, E. Stephenson, J. Engelbert, Z. K. Tuong, K. Polanski, N. Yayon, C. Xu, O. Suchanek, R. Elmentaite, , S. A. Teichmann

This study maps the developing human immune system across organs using single-cell RNA sequencing, antigen-receptor sequencing, and spatial transcriptomics, revealing cross-gestation and cross-organ variability and identifying prenatal B1 cells and unconventional T cell origins.

bioRxiv · Jan 17, 2022Immunology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology