Author

K. B. Meyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Cell Biology· 4 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 12 Research Focus:cell type annotation· 10 Assay:scRNA-seq· 9 Approach:experimental assay· 8 Research Focus:differential expression· 7 Approach:statistical model· 6 Research Focus:cell-cell communication· 4 Assay:bulk RNA-seq· 3

Frequent Co-Authors

K. Polanski· 8 shared S. A. Teichmann· 8 shared L. Mamanova· 6 shared M. R. Clatworthy· 6 shared K. Saeb-Parsy· 5 shared M. Haniffa· 5 shared R. Elmentaite· 4 shared E. Dann· 3 shared

Activity by Year

2016-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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8 shared papersImmunology

K. Polanski

Mutual co-authors in cluster

Author profile →

12 papers

Recent·Most cited

The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis

M. Woodall, A.-M. Cujba, K. B. Worlock, K.-M. Case, T. Masonou, M. Yoshida, K. Polanski, N. Huang, R. G. Lindeboom, L. Mamanova, L. Bolt, L. Richardson, S. Ellis, M. Palor, T. Burgoyne, , C. M. Smith

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

Early human lung immune cell development and its role in epithelial cell fate

J. L. Barnes, P. He, M. Yoshida, K. B. Worlock, R. G. H. Lindeboom, C. Suo, J. P. Pett, A. Wilbrey-Clark, E. Dann, L. Mamanova, L. Richardson, A. J. Oliver, A. L. Pennycuick, J. Allen-Hyttinen, I. T. Herczeg, , M. Z. Nikolic

The paper profiles lung immune cells during development using scRNAseq and identifies IL-1β's role in driving epithelial progenitor differentiation.

bioRxiv · Dec 13, 2022Immunology

Dandelion utilizes single cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

C. Suo, K. Polanski, E. Dann, R. G. H. Lindeboom, R. Vilarrasa Blasi, R. Vento-Tormo, M. Haniffa, K. B. Meyer, L. M. Dratva, Z. K. Tuong, M. R. Clatworthy, S. Teichmann

Dandelion improves V(D)J analysis in scVDJ-seq data, enabling better lineage commitment predictions and insights into lymphocyte development.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Obesity associated with attenuated tissue immune cell responses in COVID-19

S. A. Guo, G. S. Bowyer, J. R. Ferdinand, M. Maes, Z. K. Tuong, E. Gilman, M. Liao, R. G. H. Lindeboom, M. Yoshida, K. Worlock, H. Gopee, E. Stephenson, P. A. Lyons, K. G. C. Smith, M. Haniffa, , M. R. Clatworthy

The paper finds that obesity is associated with reduced immune and inflammatory responses in COVID-19 patients, including lower expression of IFN and IFNγ response genes in lung and blood cells.

bioRxiv · Jan 14, 2022 · PreprintImmunology

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

E. Madissoon, A. J. Oliver, V. Kleshchevnikov, A. Wilbrey-Clark, K. Polanski, A. E. Ribeiro Orsi, L. Mamanova, L. Bolt, J. P. Pett, N. Huang, R. Elmentaite, N. Richoz, P. He, M. Dabrowska, E. Tuck, , K. B. Meyer

The paper creates a spatial multi-omics lung atlas identifying novel cell types and a survival niche for IgA-secreting plasma cells in submucosal glands.

bioRxiv · Nov 26, 2021 · PreprintCell Biology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Integrated Single Cell Atlas of Endothelial Cells of the Human Lung

J. C. Schupp, T. S. Adams, C. Cosme, M. S. Brickman Raredon, N. Omote, S. Poli, K.-A. Rose, E. Manning, M. Sauler, G. DeIuliis, F. Ahangari, N. Neumark, Y. Yuan, A. C. Habermann, A. J. Gutierrez, , N. Kaminski

The paper reanalyzes six scRNA-seq datasets to create a comprehensive reference atlas of human lung endothelial cells, identifying new subpopulations and confirming their conservation in mice.

bioRxiv · Oct 21, 2020Cell Biology

Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

G. Kildisiute, W. M. Kholosy, M. D. Young, K. Roberts, R. Elmentaite, S. R. van Hooff, E. Khabirova, A. Piapi, C. Thevanesan, E. Bugallo Blanco, C. Burke, L. Mamanova, P. Lijnzaad, T. Margaritis, F. C. P. Holstege, , S. Behjati

The paper compares tumor and normal single-cell mRNA data to show neuroblastoma cells resemble fetal sympathoblasts across diverse samples.

bioRxiv · Jun 22, 2020Cancer Biology

A cell atlas of human thymic development defines T cell repertoire formation

J.-E. Park, R. A. Botting, C. Dominguez Conde, D.-M. Popescu, M. Lavaert, D. J. Kunz, E. Stephenson, R. Ragazzini, E. Tuck, A. L. Wilbrey-Clark, J. R. Ferdinand, S. Webb, D. Maunder, N. Vandamme, K. T. Mahbubani, , S. A. Teichmann

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

bioRxiv · Jan 28, 2020Immunology

Distinct microbial and immune niches of the human colon

K. R. James, T. Gomes, R. Elmentaite, N. Kumar, E. L. Gulliver, H. W. King, M. D. Stares, B. R. Bareham, J. R. Ferdinand, V. Petrova, K. Polanski, S. C. Forster, L. B. Jarvis, O. Suchanek, S. Howlett, , S. A. Teichmann

The paper examines microbial and immune cell interactions in the human colon, identifying distinct immune niches and T cell profiles along the colon.

bioRxiv · Dec 12, 2019Immunology

A cellular census of healthy lung and asthmatic airway wall identifies novel cell states in health and disease

F. A. Vieira Braga, G. Kar, M. Berg, O. A. Carpaij, K. Polanski, L. M. Simon, S. Brouwer, T. Gomes, L. Hesse, J. Jiang, E. S. Fasouli, M. Efremova, R. Vento-Tormo, K. Affleck, S. Palit, , S. A. Teichmann

The paper uses single-cell transcriptomics to identify novel cell states in healthy and asthmatic lung tissues, revealing changes in cell communication and immune responses.

bioRxiv · Jan 23, 2019 · PreprintImmunology

BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

I. de Santiago, W. Liu, K. Yuan, M. O'Reilly, C. S. Chilamakuri, B. A. Ponder, K. B. Meyer, F. Markowetz

BaalChIP corrects allele-specific ChIP-seq analysis for copy number variation in cancer genomes, improving detection of regulatory variants.

bioRxiv · Dec 14, 2016Cancer Biology