Author

E. Tuck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Assay:scRNA-seq· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

K. Polanski· 5 shared L. Mamanova· 4 shared E. Prigmore· 3 shared K. Saeb-Parsy· 3 shared O. Bayraktar· 3 shared S. A. Teichmann· 3 shared A. V. Predeus· 2 shared C. Dominguez Conde· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersImmunology

K. Polanski

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Author profile →

5 papers

Recent·Most cited

Single cell transcriptomics reveals chondrocyte differentiation dynamics in vivo and in vitro

J. E. G. Lawrence, S. Woods, K. Roberts, D. N. Sumanaweera, P. Balogh, A. V. Predeus, P. He, T. Li, K. Polanski, E. Prigmore, E. Tuck, L. Mamanova, D. Zhou, S. Webb, L. Jardine, , S. Teichmann

This study uses single-cell transcriptomics to compare in vitro and in vivo chondrocyte differentiation, identifies off-target differentiation, and improves in vitro protocols by inhibiting FOXO1.

bioRxiv · Dec 20, 2023Bioengineering

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

E. Madissoon, A. J. Oliver, V. Kleshchevnikov, A. Wilbrey-Clark, K. Polanski, A. E. Ribeiro Orsi, L. Mamanova, L. Bolt, J. P. Pett, N. Huang, R. Elmentaite, N. Richoz, P. He, M. Dabrowska, E. Tuck, , K. B. Meyer

The paper creates a spatial multi-omics lung atlas identifying novel cell types and a survival niche for IgA-secreting plasma cells in submucosal glands.

bioRxiv · Nov 26, 2021 · PreprintCell Biology

Cross-tissue immune cell analysis reveals tissue-specific adaptations and clonal architecture across the human body

C. Dominguez Conde, T. Gomes, L. B. Jarvis, C. Xu, S. Howlett, D. Rainbow, O. Suchanek, H. King, L. Mamanova, K. Polanski, N. Huang, E. Fasouli, K. Mahbubani, M. Prete, E. Tuck, , S. A. Teichmann

The paper analyzes immune cell diversity across 15 human tissues using single-cell RNA sequencing and VDJ sequencing, revealing tissue-specific features and clonal architecture of T and B cells.

bioRxiv · Apr 28, 2021Immunology

A cell atlas of human thymic development defines T cell repertoire formation

J.-E. Park, R. A. Botting, C. Dominguez Conde, D.-M. Popescu, M. Lavaert, D. J. Kunz, E. Stephenson, R. Ragazzini, E. Tuck, A. L. Wilbrey-Clark, J. R. Ferdinand, S. Webb, D. Maunder, N. Vandamme, K. T. Mahbubani, , S. A. Teichmann

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

bioRxiv · Jan 28, 2020Immunology