Author

M. Dabrowska

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

K. Polanski· 3 shared M. Patel· 3 shared E. Dann· 2 shared E. Prigmore· 2 shared E. Stephenson· 2 shared E. Tuck· 2 shared J. Engelbert· 2 shared K. B. Meyer· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

K. Polanski

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Author profile →

5 papers

Recent·Most cited

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

E. Madissoon, A. J. Oliver, V. Kleshchevnikov, A. Wilbrey-Clark, K. Polanski, A. E. Ribeiro Orsi, L. Mamanova, L. Bolt, J. P. Pett, N. Huang, R. Elmentaite, N. Richoz, P. He, M. Dabrowska, E. Tuck, , K. B. Meyer

The paper creates a spatial multi-omics lung atlas identifying novel cell types and a survival niche for IgA-secreting plasma cells in submucosal glands.

bioRxiv · Nov 26, 2021 · PreprintCell Biology

ESCRT-I controls lysosomal membrane protein homeostasis and restricts MCOLN1-dependent TFEB/TFE3 signaling.

M. Wrobel, E. Szymanska, N. Budick-Harmelin, K. Kolmus, K. Goryca, M. Dabrowska, A. Paziewska, M. Mikula, J. Cendrowski, M. Miaczynska

This study shows ESCRT-I regulates lysosomal membrane protein homeostasis and modulates TFEB/TFE3 signaling through MCOLN1-dependent Ca2+ channels.

bioRxiv · Jul 26, 2021 · PreprintCell Biology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Lung, spleen and oesophagus tissue remains stable for scRNAseq in cold preservation

Elo Madissoon, Anna Wilbrey-Clark, Ricardo J. Miragaia, Kourosh Saeb‐Parsy, Krishnaa T. A. Mahbubani, Nikitas Georgakopoulos, P. Harding, Krzysztof Polański, Karol Nowicki-Osuch, Rebecca Claire Fitzgerald, Kevin W. Loudon, John Robert Ferdinand, Menna Ruth Clatworthy, A. Tsingene, Stijn van Dongen, , Kerstin B. Meyer

This study evaluates the impact of cold storage on scRNAseq data quality for lung, spleen, and oesophagus tissues, finding minimal effects within 24 hours but increased stress markers at 72 hours.

bioRxiv · Aug 31, 2019 · PreprintGenomics