Cancer BiologybioRxivPreprint
9p21 Loss Defines the Evolutionary Patterns of Aggressive Renal Cell Carcinomas
F. Carbone, J. K. Huang, L. Perelli…·G. Genovese
This study establishes a mouse model of renal cell carcinoma showing that 9p21 loss drives aggressive tumor evolution with chromosomal instability and metastasis.
DOI 10.1101/2020.11.03.367433