Author

F. Carbone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Carugo· 3 shared A. Viale· 3 shared G. Genovese· 3 shared A. Futreal· 2 shared A. Sgambato· 2 shared B. P. Perot· 2 shared C. de Cevins· 2 shared C. Zhu· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

A. Carugo

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Author profile →

5 papers

Recent·Most cited

Evolutionary fingerprints of EMT in pancreatic cancers

L. Perelli, L. Zhang, S. Mangiameli, A. J. C. Russell, F. Giannese, F. Peng, F. Carbone, C. Le, H. Khan, F. Citron, M. Soeung, T. Lam, S. Lundgren, C. Zhu, D. Catania, , G. Genovese

This study investigates the role of EMT in pancreatic cancer evolution and metastasis, showing that mesenchymal lineages drive chromosomal instability and clonal evolution.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

Enhanced inflammatory signaling driven by metabolic switch in Aicardi-Goutieres syndrome

M. Batignes, M. Luka, S. Jagtap, C. de Cevins, I. Nemazanyy, T. Fali, V. Garcia-Paredes, F. Carbone, B. P. Perot, B. Neven, B. Bader-Meunier, P. Quartier dit Maire, M. Hully, A. Belot, A. Lepelley, , M. M. Menager

This study identifies a metabolic switch and loss of HIF-1 activity in AGS patients, showing that stabilizing HIF-1 reduces inflammation and IP-10 production.

bioRxiv · Feb 23, 2023 · PreprintImmunology

A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis

C. de Cevins, M. Luka, N. Smith, S. Meynier, A. Magerus, F. Carbone, V. Garcia Paredes, L. Barnabei, M. Batignes, A. Boulle, M.-C. Stolzenberg, B. P. Perot, B. Charbit, T. Fali, V. Pirabarakan, , Gras Leguen

The paper identifies a monocyte/dendritic cell gene signature in severe MIS-C with myocarditis, linked to NF-κB activity and cytokine signaling.

bioRxiv · Feb 23, 2021Immunology

9p21 Loss Defines the Evolutionary Patterns of Aggressive Renal Cell Carcinomas

F. Carbone, J. K. Huang, L. Perelli, E. Del Poggetto, T. Gutschner, H. Tomihara, M. Soeung, T. N. A. Lam, R. Xia, C. Zhu, X. Song, J. Zhang, K. Sircar, G. G. Malouf, A. Sgambato, , G. Genovese

This study establishes a mouse model of renal cell carcinoma showing that 9p21 loss drives aggressive tumor evolution with chromosomal instability and metastasis.

bioRxiv · Nov 3, 2020 · PreprintCancer Biology

Medium-chain acyl-CoA dehydrogenase, a gatekeeper of mitochondrial function in glioblastoma multiforme

F. Puca, F. Yu, C. Bertolacci, P. Pettazzoni, A. Carugo, E. Huang-Hobbs, J. Liu, C. Zanca, F. Carbone, E. Del Poggetto, J. Gumin, P. Dasgupta, S. Seth, F. F. Lang, E. Sulman, , G. Draetta

This study identifies MCAD as a critical enzyme for fatty acid metabolism in GBM, showing its essential role in preventing mitochondrial damage and apoptosis.

bioRxiv · Sep 28, 2020 · PreprintCancer Biology