Author

E. Downs-Kelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Caputo· 1 shared A. Farrell· 1 shared A. H. Bild· 1 shared A. L. Cohen· 1 shared A. Myers· 1 shared B. Hu· 1 shared C. Eng· 1 shared D. F. Jenkins· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Caputo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics

A. Caputo, K. Vipparthi, P. Bazeley, E. Downs-Kelly, P. McIntire, Y. Ni, B. Hu, R. A. Keri, M. Karaayvaz

This study uses spatial transcriptomics to identify microenvironmental and signaling differences in preneoplastic breast tissues of BRCA1/2 mutation carriers compared to non-carriers.

bioRxiv · May 24, 2023 · PreprintCancer Biology

Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell Penetrating Peptides in Triple Negative Breast Cancers

E. E. Mulkearns-Hubert, E. Esakov, S. Ben-Salem, R. Bharti, N. Hajdari, S. Johnson, A. Myers, I. N. Smith, S. Bandyopadhyay, C. Eng, E. Downs-Kelly, J. Lathia, O. Reizes

This study demonstrates that a cell-penetrating peptide targeting the Cx26/NANOG/FAK complex inhibits tumor growth and alters NANOG activity in triple-negative breast cancer.

bioRxiv · Sep 9, 2021 · PreprintCancer Biology

Novel temporal and spatial patterns of metastatic colonization from rapid-autopsy tumor biopsies

X. Huang, Y. Qiao, S. W. Brady, R. E. Factor, E. Downs-Kelly, A. Farrell, J. A. McQuerry, G. Shrestha, D. F. Jenkins, W. E. Johnson, A. L. Cohen, A. H. Bild, G. T. Marth

This study uses rapid autopsy and whole genome sequencing to analyze metastatic evolution in a patient, identifying subclone incubators and four waves of metastatic expansion.

bioRxiv · Jun 3, 2021Cancer Biology