Author

Y. Ni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 4 Biophysics· 2 Biochemistry· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 11 Organism:human· 5 Research Focus:differential expression· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 3 Assay:proteomics· 3 Approach:statistical model· 3

Frequent Co-Authors

J. Li· 4 shared B. Cao· 2 shared D. Chen· 2 shared G. Niu· 2 shared J. Ni· 2 shared L. Zhang· 2 shared M. Yang· 2 shared T. Xia· 2 shared

Activity by Year

2017-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersBioengineering

J. Li

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14 papers

Recent·Most cited

Low-intensity transcranial focused ultrasound suppresses pain by modulating pain processing brain circuits

M. G. Kim, K. Yu, C.-Y. Yeh, R. Fouda, D. Argueta, S. Kiven, Y. Ni, X. Niu, Q. Chen, K. Kim, K. Gupta, B. He

This paper demonstrates that low-intensity transcranial focused ultrasound can suppress pain by modulating pain processing brain circuits in mouse models.

Blood · Sep 5, 2024Peer-reviewedBioengineering

The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells

C. Pan, Y. Liu, L. Wang, W. Fan, Y. Ni, X. Zhang, D. Wu, C. Li, J. Li, Z. Li, R. Liu, C. Hu

This study shows PGE2 inhibits glucose-stimulated insulin secretion in β-cells via the EP2/4-Kv2.2 pathway by modulating Kv2.2 channels through PKA.

bioRxiv · Mar 11, 2024Physiology

Social Rank Alters the Synchrony of Attribute Integration in Altruistic Decisions

Y. Ni, J. Li

This study investigates how social rank affects the integration of attributes in altruistic decisions, finding that social rank modulates attribute timing but not weights.

bioRxiv · Oct 26, 2023 · PreprintNeuroscience

Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics

A. Caputo, K. Vipparthi, P. Bazeley, E. Downs-Kelly, P. McIntire, Y. Ni, B. Hu, R. A. Keri, M. Karaayvaz

This study uses spatial transcriptomics to identify microenvironmental and signaling differences in preneoplastic breast tissues of BRCA1/2 mutation carriers compared to non-carriers.

bioRxiv · May 24, 2023 · PreprintCancer Biology

Identification and calibration of ultrabright localizations to eliminate quantification error in SMLM

B. Cao, J. Ni, G. Niu, D. Chen, G. Liu, L. Zhou, T. Xia, F. Feng, S. Wei, X. Yuan, Y. Ni

This paper identifies and calibrates ultrabright localizations in SMLM to improve quantification accuracy for biomolecular organization.

bioRxiv · Apr 6, 2022 · PreprintBiophysics

Nanobody-Functionalized Cellulose for Capturing and Containing SARS-CoV-2

X. Sun, S. Yang, A. Al-Dossary, S. Broitman, Y. Ni, M. Yang, J. Li

This paper develops a cellulose-based method using nanobodies to capture and neutralize SARS-CoV-2 pseudoviruses, showing effectiveness against wildtype and D614G variants.

bioRxiv · Sep 1, 2021Bioengineering

Spatial transcriptome sequencing revealed spatial trajectory in the Non-Small Cell Lung Carcinoma

L. Zhang, S. Mao, M. Yao, N. Chao, Y. Yang, T. Song, Y. Ni, Z. Liu, Y. Yang, W. Li

The paper uses spatial transcriptomics to analyze lung cancer heterogeneity, identifying gene expression gradients and tumor subclones, and infers metastasis trajectories through pseudo-time modeling.

bioRxiv · Apr 26, 2021 · PreprintCancer Biology

New metabolic alterations and predictive marker pipecolic acid in sera for esophageal squamous cell carcinoma

L. Liu, J. Wu, M. Shi, F. Wang, H. Lu, J. Liu, W. Chen, G. Yu, D. Liu, J. Yang, Q. Luo, Y. Ni, X. Jin, X. Jin, W.-L. Chen

This study identifies 12 serum metabolites associated with esophageal squamous cell carcinoma and highlights pipecolic acid as a predictive biomarker for tumorigenesis.

bioRxiv · Mar 31, 2021Cancer Biology

Improving localization precision via restricting biomolecule confined stochastic motion in SMLM

J. Ni, B. Cao, G. Niu, T. Xia, D. Chen, W. Zhang, Y. Zhang, X. Yuan, Y. Ni

This study investigates stochastic motion of biomolecules in SMLM and shows that restricting this motion improves localization precision.

bioRxiv · Mar 16, 2021Biophysics

Engineering the Immune Adaptor Protein STING as a Biologic

X. Sun, Y. Ni, Y. He, M. Yang, T. Tani, S. Kitajima, D. A. Barbie, J. Li

This study engineers the STING protein as a delivery system to enhance CDN delivery and restore STING signaling in cancer cells.

bioRxiv · Feb 18, 2021 · PreprintBioengineering

RAPPID: a platform of ratiometric bioluminescent sensors for homogeneous immunoassays

Y. Ni, B. J. H. M. Rosier, E. A. van Aalen, E. T. L. Hanckmann, L. Biewenga, A.-M. Makri Pistikou, B. Timmermans, C. Vu, S. Roos, R. Arts, W. Li, T. F. A. de Greef, F. J. M. van Kuppeveld, B.-J. Bosch, M. Merkx

RAPPID is a homogeneous immunoassay platform using ratiometric bioluminescent sensors for direct in-sample calibration and quantitative detection of biomarkers.

bioRxiv · Oct 31, 2020 · PreprintBioengineering

An RNA-based system to study hepatitis B virus replication and select drug-resistance mutations

Y. Yu, W. M. Schneider, E. Michailidis, A. Acevedo, Y. Ni, P. Ambrose, C. Zou, M. Kabbani, C. Quirk, C. Jahan, X. Wu, S. Urban, A. Shlomai, Y. P. de Jong, C. M. Rice

This paper describes an RNA-based system to study HBV replication and predict drug resistance mutations.

bioRxiv · Oct 2, 2019 · PreprintMicrobiology

Dynamic urinary proteomic analysis in a Walker 256 intracerebral tumor model

L. Zhang, Y. Li, W. Meng, Y. Ni, Y. Gao

The paper analyzes urinary proteomic changes in a rat brain tumor model to identify early biomarkers of tumor progression and differences between tumor growth locations.

bioRxiv · Dec 2, 2018Cancer Biology

Early Candidate Biomarkers Found From Urine Of Astrocytoma Rat Before Changes In MRI

Y. Ni, F. Zhang, M. An, W. Yin, Y. Gao

The paper identifies early urinary biomarkers for astrocytoma in rats before MRI changes, using proteomic analysis of urine samples collected at different time points post-tumor induction.

bioRxiv · Apr 1, 2017Biochemistry